• Fully of FDA approved anti

  2019-07-06

  

  Fully 50% of FDA-approved anti-cancer drugs are ROS-generating agents [2], and ROS can compromise the BBB by triggering several pathways, including oxidative stress [54]. Increased BBB permeability and disruption allow peripheral toxins and inflammatory mediators able to go into Omadacycline chemica

• br Conclusion br Conflicts of interest br

  2019-07-06

  

  Conclusion Conflicts of interest Transparency document Acknowledgements This study was supported by grants from the Shanghai Municipal Health and Family Planning Commission Foundation (No. 2016ZB0306) and the National Natural Science Foundation of China (No. 81773719, No. 81703590). I

• While mass spectrometry is now routinely utilized

  2019-07-05

  

  While mass spectrometry is now routinely utilized to investigate PTMs, it is more often times used for the development of antibodies and antibody-enrichment strategies for the observation of PTMs with low site occupancy [36]. This is particularly important when the sample medium becomes complex, suc

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