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br Analysis br Unadjusted counts of papillary
2021-03-10
Analysis Unadjusted counts of papillary thyroid cases and age-adjusted incidence rates per 100,000 with 95% confidence intervals were calculated using SEER*Stat 8.3.4).38 The incidence rates were standardized to the US 2000 population. In addition, we also computed proportions of various surger
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br Fig IGF BP binds
2021-03-03
Fig. 3. IGF2BP3 binds to TRIM25 mRNA and inhibits miR-3614 maturation in BC cells. (a) Proposed model of IGF2BP3, HuR and miR-3614 Trichostatin A (TSA) at the TRIM25 mRNA 3′-UTR. (b–e) The levels of IGF2BP3 mRNA, TRIM25 mRNA, pri-miR-3614 and miR-3614-3p were determined by qRT–PCR after BC cells
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br sensitively detected in transformed ORGs but not
2021-03-03
sensitively detected in transformed ORGs, but not wild ORGs. Higher GLuc levels were measured in medium of ORGKrasG12D/P53Del versus that of ORGKrasG12D (Fig. 3E). GLuc levels in transformed ORGs were highly correlative with BIRC5 expression, as determined by Western blot (R = 0.97) (Fig. 3F an
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br Lung cancer cells with a higher
2021-03-03
Lung cancer Dihexa (PNB-0408) with a higher level of OCT4 are more resistant to drug treatments [58]. Regarding cancer stemness, OCT4 and CD44 are both representative stemness markers for several cancers. In the present study, the expression of OCT4 was up-regulated and CD44 was down- regulate
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br For comparison type I collagenecoated plates were prepare
2020-08-30
For comparison, type I collagenecoated plates were prepared by adding Cellmatrix I-C solution onto 24-well tissue culture plates (TCPs) and heated at 37 C for 2 h. Then, the added solution was removed. 2.3. Characterization Rheological measurements were conducted using a RDAII in-strument wi
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br Transplantation of the non
2020-08-30
Transplantation of the non-tumorigenic human embryonic kidney (HEK) 293 Brefeldin-A that stably express CD133 into SCID mice resulted in tumor formation (Canis et al., 2013). It clearly showed that CD133 is sufficient to initiate tumorigenesis. Overexpression of CD133 in cul-tured human pancreatic
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D IKK Results were calculated as protein actin ratio and
2020-08-30
(D) IKKγ. Results were calculated as protein/β-actin ratio and presented as mean percent of the CL-siScr with SD. Statistical analysis: student t test: (treatment vs. siScr: ****P b 0.0001, treatment vs. cisplatin: ##P b 0.01; ###P b 0.001; ####P b 0.0001, and treatment vs. CL-siSOX2: ††††P b 0.0001
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br Cardiovascular disease particularly previous
2020-08-28
Cardiovascular disease (particularly previous myocardial infarction and valvular disease) greatly increases the risk for toxicities, particularly in patients receiving anthracycline-based chemotherapies [16–18]. The relation of risk factors to side effects from the novel therapies (molecu-larly ta
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br Secondary analysis br If analyses
2020-08-28
3.4. Secondary analysis If analyses were extended to exposure/cancer site pairs where there is limited evidence of a causal relationship, then 12,314 new cancer cases, representing 3.5% of all new cancer cases, were estimated to be attributable to occupational agents in France in 2015 (Ta
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br further experiments using patient derived primary
2020-08-28
further experiments using patient-derived primary human GBM cell line GBM1A. GBM1A, which is capable of forming measurable mass-effect tumors when injected orthotopically, mimics what is seen in the clinic and is complimentary to GBM line 612. GBM1A SCH58261 were transfected with a mixture of five
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br Phase br Phase education which started immediately
2020-08-28
Phase 2 Phase 2 education, which started immediately following phase 1, was provided to adolescents and their parents by the pro- viders and staff at each study site. The education included dis-tributing the cancer prevention awareness booklets to all adolescents and their parents who cam
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br mice Supplementary Fig A C In
2020-08-28
mice (Supplementary Fig. 1A-C). In addition, BCF decreased the tumour growth in Paclitaxel when SKBrM3 cells were orthotopically implanted in the brain (Fig. 1D). We also implanted triple negative brain metastatic variant 231-BrM cells both systemically (Fig. 1E-F) and orthotopically (Fig. 1G),
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br The th th and
2020-08-24
The 12th, 13th and 14th (2011, 2013 and 2015) St Gallen International Breast Cancer Conference Expert Panel adopted a new approach to the classification of patients for therapeutic purposes based on the recognition of intrinsic biological subtypes within the breast cancer spectrum (Luminal A, Lumi
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mura et al Schmidlin et al These studies The three
2020-08-18
mura et al., 2016; Schmidlin et al., 2016). These studies The three key Voriconazole identified by our decision tree are strongly include our recent comparison of S/MRM, pseudo-SRM/ associated with important clinical parameters, namely ER status MRMHR, and SWATH-MS analytical parameters i
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br Abbreviations C consented NC non consented
2020-08-18
Abbreviations: C, consented; NC, non-consented; DCIS, ductal carcinoma in situ; LCIS, lobular carcinoma in situ; NHI, National Health Index number Corresponding author. E-mail address: [email protected] (J.M. Elwood). Table 1 Disease specific survival up to 10 years in consent